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Melatonin has been trialled many times and has been found to be successful in alleviating jet lag. However there are concerns over the continued use of melatonin supplements. Some countries have made melatonin supplements prescription only.
Melatonin has commonly been used to regulate sleep patterns in cases of jet lag and insomnia. Less well known are its uses as a natural antioxidant and immune system booster. It can also increase the frequency of lucid dreaming.
Several trials have demonstrated the stimulation of the pineal gland using brainwave entrainment. Very specific frequencies in the delta brainwave range are thought to be responsible for this stimulation.